Baclofen and Vecuronium interaction

Baclofen and Vecuronium: the Vecuronium prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Vecuronium (Vecuronium Bromide) label · effective 2026-03-19

Moderate

In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants.

Warningsby drug classView label on DailyMed
Minor

There are insufficient data to support concomitant use of vecuronium and other competitive muscle relaxants in the same patient.

Drug interactionsby drug classView label on DailyMed
Minor

Other Experience concerning injection of quinidine during recovery from use of other muscle relaxants suggests that recurrent paralysis may occur.

Precautionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.