Benztropine and Dextromethorphan and quinidine interaction

Benztropine and Dextromethorphan and quinidine: the Dextromethorphan and quinidine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Dextromethorphan and quinidine (Nuedexta) label · effective 2026-01-22

Moderate

Anticholinergic effects of quinidine: Monitor for worsening in myasthenia gravis and other sensitive conditions.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Anticholinergic Effects of Q uinidine Monitor for worsening clinical condition in myasthenia gravis and other conditions that may be adversely affected by anticholinergic effects.

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.