Bismuth subcitrate, metronidazole, and tetracycline and Metronidazole interaction

Bismuth subcitrate, metronidazole, and tetracycline and Metronidazole: the Metronidazole prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Metronidazole (LIKMEZ) label · effective 2025-04-18

Moderate

Warfarin and other Oral Anticoagulants Metronidazole has been reported to potentiate the anticoagulant effect of warfarin and other oral coumarin anticoagulants, resulting in a prolongation of prothrombin time.

Drug interactionsnames Bismuth subcitrate, metronidazole, and tetracyclineView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.