Bisoprolol and hydrochlorothiazide and Butorphanol interaction

Bisoprolol and hydrochlorothiazide and Butorphanol: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Bisoprolol and hydrochlorothiazide (bisoprolol fumarate and hydrochlorothiazide) label · effective 2026-08-11

Moderate

Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur.

Precautionsby drug classView label on DailyMed

From the Butorphanol (Butorphanol Tartrate) label · effective 2026-01-02

Minor

In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive drugs.

Warningsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.