Brincidofovir and Cidofovir interaction
Brincidofovir and Cidofovir: the Brincidofovir prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.
Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.
What the FDA labels say
From the Brincidofovir (Tembexa) label · effective 2025-07-23
• Coadministration with Related Products: TEMBEXA should not be coadministered with intravenous cidofovir.
Coadministration with Related Products TEMBEXA should not be co-administered with intravenous cidofovir.
Brincidofovir, a lipid-linked derivative of cidofovir, is intracellularly converted to cidofovir [see Clinical Pharmacology ( 12.3 )] .
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.