Brivaracetam and Chlorpromazine interaction

Brivaracetam and Chlorpromazine: the Chlorpromazine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Chlorpromazine (Chlorpromazine Hydrochloride) label · effective 2026-02-02

Moderate

Therefore, dosage of anticonvulsants, including barbiturates, should not be reduced if chlorpromazine is started.

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Moderate

Chlorpromazine may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary.

Precautionsby drug classView label on DailyMed
Minor

Note: Chlorpromazine does not intensify the anticonvulsant action of barbiturates.

Precautionsby drug classView label on DailyMed
Minor

Potentiation of anticonvulsant effects does not occur.

Precautionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.