Budesonide and formoterol and Mirabegron interaction

Budesonide and formoterol and Mirabegron: the Budesonide and formoterol prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Budesonide and formoterol (Budesonide and Formoterol Fumarate Dihydrate) label · effective 2026-04-24

Major

Use with additional long-acting beta 2 -agonist: Do not use in combination because of risk of overdose.

Warnings and precautionsby drug classView label on DailyMed
Major

Clinically significant cardiovascular effects and fatalities have been reported in association with excessive use of inhaled sympathomimetic drugs.

Warnings and precautionsby drug classView label on DailyMed
Major

Fatalities have been reported in association with excessive use of inhaled sympathomimetic drugs.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Serious asthma-related events: Long-acting beta2-adrenergic agonists as monotherapy increase the risk.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Strong cytochrome P450 3A4 inhibitors (e.g., ritonavir): Risk of increased systemic corticosteroid effects.

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.