Butalbital, aspirin, and caffeine and Sildenafil interaction

Butalbital, aspirin, and caffeine and Sildenafil: the Sildenafil prescribing label reports no clinically significant interaction between these two.

No interaction

No clinically significant interaction reported. The label studied or considered this pair and found nothing meaningful.

What the FDA labels say

From the Sildenafil label · effective 2026-07-17

No interaction

In humans, sildenafil has no effect on bleeding time when taken alone or with aspirin.

Warnings and precautionsnames Butalbital, aspirin, and caffeineView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.