Butorphanol and Pyridostigmine interaction

Butorphanol and Pyridostigmine: the Pyridostigmine prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Pyridostigmine (Pyridostigmine bromide) label · effective 2026-05-13

Minor

Narcotics: Exacerbation of bradycardia possible.

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Minor

Narcotics The bradycardia associated with the use of narcotics may exacerbate pyridostigmine-induced bradycardia.

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.