Calcitriol and Spironolactone and hydrochlorothiazide interaction
Calcitriol and Spironolactone and hydrochlorothiazide: the Calcitriol prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Calcitriol label · effective 2026-07-10
Thiazides Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine.
Some reports have shown that the concomitant administration of thiazides with calcitriol causes hypercalcemia.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.