Candesartan and Nifedipine interaction

Candesartan and Nifedipine: the Nifedipine prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Nifedipine label · effective 2026-02-05

Minor

Candesartan: No significant drug interaction has been reported in studies with candesartan cilexitil given together with nifedipine.

Drug interactionsnames CandesartanView label on DailyMed
No interaction

Because candesartan is not significantly metabolized by the cytochrome P450 system and at therapeutic concentrations has no effect on cytochrome P450 enzymes, interactions with drugs that inhibit or are metabolized by those enzymes would not be expected.

Drug interactionsnames CandesartanView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.