Carbinoxamine and Selegiline interaction

Carbinoxamine and Selegiline: the Carbinoxamine prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Carbinoxamine (Carbinoxamine Maleate Extended-Release Oral Suspension) label · effective 2026-03-12

Major

…because deaths have been reported in this age group [see Warnings and Precautions (5.1)]. patients who are hypersensitive to carbinoxamine maleate or any of the inactive ingredients in Carbinoxamine Maleate Extended-Release Oral Suspension [see Warnings and Precautions (5.4)]. patients who are taking monoamine oxidase inhibitors (MAOI) [see Drug Interactions (7)].

Contraindicationsby drug classView label on DailyMed
Major

Monoamine oxidase inhibitors (MAOI) (4)

Contraindicationsby drug classView label on DailyMed
Major

Do not use Carbinoxamine Maleate extended-release oral suspension in patients who are taking monoamine oxidase inhibitors (MAOIs), which prolong and intensify the anticholinergic (drying) effects of antihistamines.

Drug interactionsby drug classView label on DailyMed
Moderate

Monoamine oxidase inhibitors (MAOIs): Prolong and intensify the anticholinergic (drying) effects.

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.