Carisoprodol and Selegiline interaction

Carisoprodol and Selegiline: the Selegiline prescribing label flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Selegiline (ZELAPAR) label · effective 2021-06-01

Major

John’s wort or cyclobenzaprine (a tricyclic muscle relaxant).

Contraindicationsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.