Cefprozil and Probenecid and colchicine interaction
Cefprozil and Probenecid and colchicine: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Probenecid and colchicine label · effective 2026-01-27
DRUG INTERACTIONS When probenecid is used to elevate plasma concentrations of penicillin, or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug.
In the case of penicillin, or other beta-lactams, psychic disturbances have been reported.
From the Cefprozil label · effective 2026-07-09
Concomitant administration of probenecid doubled the AUC for cefprozil.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.