Ceftriaxone and Vancomycin interaction

Ceftriaxone and Vancomycin: the Ceftriaxone prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Ceftriaxone (CEFTRIAXONE AND DEXTROSE) label · effective 2022-01-13

Moderate

Vancomycin, Amsacrine, Aminoglycosides, and Fluconazole Vancomycin, amsacrine, aminoglycosides, and fluconazole are physically incompatible with ceftriaxone in admixtures [see Dosage and Administration (2.3) ].

Drug interactionsnames VancomycinView label on DailyMed
Minor

Vancomycin, amsacrine, aminoglycosides, and fluconazole are physically incompatible.

Drug interactionsnames VancomycinView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.