Cetirizine and Efavirenz interaction

Cetirizine and Efavirenz: the Efavirenz prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Efavirenz label · effective 2024-03-31

Moderate

Prophylaxis with appropriate antihistamines before initiating therapy with efavirenz in pediatric patients should be considered.

Warnings and precautionsby drug classView label on DailyMed
Minor

Appropriate antihistamines and/or corticosteroids may improve the tolerability and hasten the resolution of rash.

Warnings and precautionsby drug classView label on DailyMed
No interaction

…Clinically Significant Interactions with Efavirenz No dosage adjustment is recommended when efavirenz is given with the following: aluminum/magnesium hydroxide antacids, azithromycin, cetirizine, famotidine, fluconazole, lorazepam, nelfinavir, nucleoside reverse transcriptase inhibitors (abacavir, emtricitabine, lamivudine, stavudine, tenofovir disoproxil fumarate,…

Drug interactionsnames CetirizineView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.