Cevimeline and Paroxetine interaction

Cevimeline and Paroxetine: the Cevimeline prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Cevimeline (Cevimeline Hydrochloride) label · effective 2026-01-31

Minor

Cevimeline might interfere with desirable antimuscarinic effects of drugs used concomitantly.

Drug interactionsby drug classView label on DailyMed
Minor

Drugs which inhibit CYP2D6 and CYP3A3/4 also inhibit the metabolism of cevimeline.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.