Chlordiazepoxide and clidinium and Clorazepate interaction
Chlordiazepoxide and clidinium and Clorazepate: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Chlordiazepoxide and clidinium (Librax) label · effective 2023-01-13
Effects on the Ability to Drive or Operate Machinery As in the case of other preparations containing CNS-acting drugs, patients receiving Librax should be cautioned about possible combined effects with opioids, alcohol and other CNS depressants.
However, there are reports of sedation, poor feeding and poor weight gain in infants exposed to other benzodiazepines through breast milk.
From the Clorazepate (Clorazepate Dipotassium) label · effective 2026-07-24
Although early studies reported an increased risk of congenital malformations with diazepam and chlordiazepoxide, there was no consistent pattern noted.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.