Chlordiazepoxide and Clorazepate interaction

Chlordiazepoxide and Clorazepate: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Chlordiazepoxide (CHLORDIAZEPOXIDE HYDROCHLORIDE) label · effective 2023-02-07

Moderate

The concomitant use of alcohol or other central nervous system depressants may have an additive effect.

Warningsby drug classView label on DailyMed

From the Clorazepate (Clorazepate Dipotassium) label · effective 2026-07-24

Moderate

Although early studies reported an increased risk of congenital malformations with diazepam and chlordiazepoxide, there was no consistent pattern noted.

Drug interactionsnames ChlordiazepoxideView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.