Chloroquine and Cyclosporine interaction

Chloroquine and Cyclosporine: the Chloroquine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Chloroquine (Chloroquine Phosphate) label · effective 2026-01-13

Moderate

Cyclosporine: After introduction of chloroquine (oral form), a sudden increase in serum cyclosporine level has been reported.

Drug interactionsnames CyclosporineView label on DailyMed
Moderate

Therefore, close monitoring of serum cyclosporine level is recommended and, if necessary, chloroquine should be discontinued.

Drug interactionsnames CyclosporineView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.