Chlorpromazine and Propranolol interaction
Chlorpromazine and Propranolol: the Chlorpromazine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Chlorpromazine (Chlorpromazine Hydrochloride) label · effective 2026-02-02
Concomitant administration with propranolol results in increased plasma levels of both drugs.
Chlorpromazine may counteract the antihypertensive effect of guanethidine and related compounds.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.