Cimetidine and Ofloxacin interaction

Cimetidine and Ofloxacin: the Ofloxacin prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Ofloxacin label · effective 2026-06-06

Minor

Cimetidine Cimetidine has demonstrated interference with the elimination of some quinolones.

Drug interactionsnames CimetidineView label on DailyMed
Minor

The potential for interaction between ofloxacin and cimetidine has not been studied.

Drug interactionsnames CimetidineView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.