Cisatracurium and Succinylcholine interaction

Cisatracurium and Succinylcholine: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Succinylcholine (QUELICIN) label · effective 2026-08-18

Moderate

If other neuromuscular blocking agents are to be used during the same procedure, consider the possibility of a synergistic or antagonistic effect.

Drug interactionsby drug classView label on DailyMed
Minor

Therefore, assess patients for previous anaphylactic reactions to other neuromuscular blocking agents before administering QUELICIN.

Warnings and precautionsby drug classView label on DailyMed

From the Cisatracurium (Cisatracurium Besylate) label · effective 2026-06-30

Moderate

Succinylcholine : May decrease time to onset of maximum neuromuscular blockade ( 7.1 )

Drug interactionsnames SuccinylcholineView label on DailyMed
Moderate

Precautions should also be taken in those patients who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported.

Warnings and precautionsby drug classView label on DailyMed
No interaction

…administration. † Examples: aminoglycosides, tetracyclines, bacitracin, polymyxins, lincomycin, clindamycin, colistin, sodium colistimethate Drug or Drug Class Clinical Implications * Succinylcholine The use of succinylcholine prior to Cisatracurium Besylate Injection administration may decrease the time to onset of maximum neuromuscular blockade but has no effect…

Drug interactionsnames SuccinylcholineView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.