Cisplatin and Rituximab interaction

Cisplatin and Rituximab: the Rituximab prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Rituximab (Riabni) label · effective 2026-07-22

Moderate

Renal toxicity has occurred in patients who experience tumor lysis syndrome and in patients with NHL administered concomitant cisplatin therapy during clinical trials.

Warnings and precautionsnames CisplatinView label on DailyMed
Moderate

Renal toxicity when used in combination with cisplatin ( 5.8 ).

Drug interactionsnames CisplatinView label on DailyMed
Minor

The combination of cisplatin and RIABNI is not an approved treatment regimen.

Warnings and precautionsnames CisplatinView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.