Colesevelam and Lomitapide interaction
Colesevelam and Lomitapide: the Lomitapide prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Lomitapide (Juxtapid) label · effective 2026-01-20
Bile Acid Sequestrants: Separate JUXTAPID dosing by at least 4 hours ( 7.6 ).
Administration of JUXTAPID and bile acid sequestrants should be separated by at least 4 hours since bile acid sequestrants can interfere with the absorption of oral medications.
Bile Acid Sequestrants JUXTAPID has not been tested for interaction with bile acid sequestrants.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.