Conjugated estrogens and Testosterone interaction

Conjugated estrogens and Testosterone: the Conjugated estrogens prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Conjugated estrogens (Premarin) label · effective 2025-05-30

Moderate

Free hormone concentrations, such as testosterone and estradiol, may be decreased.

Precautionsnames TestosteroneView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.