Cyclopentolate and Memantine and donepezil interaction

Cyclopentolate and Memantine and donepezil: both prescribing labels mention this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Cyclopentolate (Cyclogyl) label · effective 2024-06-25

Minor

Drug Interactions: Cyclopentolate may interfere with the ocular anti-hypertensive action of carbachol, pilocarpine, or ophthalmic cholinesterase inhibitors.

Drug interactionsby drug classView label on DailyMed

From the Memantine and donepezil (Namzaric) label · effective 2026-03-06

Minor

NAMZARIC may interfere with anticholinergic medications.

Drug interactionsby drug classView label on DailyMed
Minor

Use of Donepezil with Anticholinergics Because of their mechanism of action, cholinesterase inhibitors, including donepezil hydrochloride, have the potential to interfere with the activity of anticholinergic medications.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.