Cyclosporine and Hydroxychloroquine interaction

Cyclosporine and Hydroxychloroquine: the Hydroxychloroquine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Hydroxychloroquine (Plaquenil) label · effective 2026-04-09

Moderate

Cyclosporine An increased plasma cyclosporin level was reported when cyclosporin and PLAQUENIL were co-administered.

Drug interactionsnames CyclosporineView label on DailyMed
Moderate

Monitor serum cyclosporine levels closely in patients receiving combined therapy.

Drug interactionsnames CyclosporineView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.