Dantrolene and Succinylcholine interaction

Dantrolene and Succinylcholine: the Succinylcholine prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Succinylcholine (QUELICIN) label · effective 2026-08-18

Minor

Discontinue triggering agents, administer intravenous dantrolene sodium, and apply supportive therapies.

Warnings and precautionsnames DantroleneView label on DailyMed
Minor

If malignant hyperthermia is suspected, discontinue all triggering agents (i.e., volatile anesthetic agents and succinylcholine), administer intravenous dantrolene sodium, and initiate supportive therapies.

Warnings and precautionsnames DantroleneView label on DailyMed
Minor

Consult prescribing information for intravenous dantrolene sodium for additional information on patient management.

Warnings and precautionsnames DantroleneView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.