Darifenacin and Warfarin interaction

Darifenacin and Warfarin: the Darifenacin prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Darifenacin label · effective 2026-02-10

Moderate

Standard therapeutic prothrombin time monitoring for warfarin should be continued.

Drug interactionsnames WarfarinView label on DailyMed
No interaction

Warfarin Darifenacin had no significant effect on prothrombin time when a single dose of warfarin 30 mg was co-administered with darifenacin (30 mg daily) at steady-state.

Drug interactionsnames WarfarinView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.