Darunavir and Dorzolamide interaction

Darunavir and Dorzolamide: the Darunavir prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Darunavir (PREZISTA) label · effective 2025-08-29

Moderate

Use with caution in patients with a known sulfonamide allergy.

Warnings and precautionsby drug classView label on DailyMed
Moderate

PREZISTA should be used with caution in patients with a known sulfonamide allergy.

Warnings and precautionsby drug classView label on DailyMed
Minor

Sulfa Allergy Darunavir contains a sulfonamide moiety.

Warnings and precautionsby drug classView label on DailyMed
Minor

In clinical studies with PREZISTA/ritonavir, the incidence and severity of rash were similar in subjects with or without a history of sulfonamide allergy.

Warnings and precautionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.