Darunavir and Methazolamide interaction
Darunavir and Methazolamide: the Darunavir prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Darunavir (PREZISTA) label · effective 2025-08-29
Use with caution in patients with a known sulfonamide allergy.
PREZISTA should be used with caution in patients with a known sulfonamide allergy.
Sulfa Allergy Darunavir contains a sulfonamide moiety.
In clinical studies with PREZISTA/ritonavir, the incidence and severity of rash were similar in subjects with or without a history of sulfonamide allergy.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.