Darunavir and Sitagliptin interaction
Darunavir and Sitagliptin: the Darunavir prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Darunavir (PREZISTA) label · effective 2025-08-29
Initiation or dose adjustments of insulin or oral hypoglycemic agents may be required.
Some patients required either initiation or dose adjustments of insulin or oral hypoglycemic agents for treatment of these events.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.