Desloratadine and Ranitidine interaction

Desloratadine and Ranitidine: the Desloratadine prescribing label reports no clinically significant interaction between these two.

No interaction

No clinically significant interaction reported. The label studied or considered this pair and found nothing meaningful.

What the FDA labels say

From the Desloratadine (Clarinex) label · effective 2025-05-17

No interaction

…safety profile of desloratadine. [See Clinical Pharmacology (12.3) .] 7.3 Cimetidine In controlled clinical studies co-administration of desloratadine with cimetidine, a histamine H2-receptor antagonist, resulted in increased plasma concentrations of desloratadine and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile…

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.