Desogestrel and ethinyl estradiol and Rosuvastatin interaction

Desogestrel and ethinyl estradiol and Rosuvastatin: the Desogestrel and ethinyl estradiol prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Desogestrel and ethinyl estradiol label · effective 2026-06-24

Moderate

Substances increasing the plasma concentrations of COCs: Co-administration of atorvastatin or rosuvastatin and certain COCs containing EE increase AUC values for EE by approximately 20 to 25%.

Drug interactionsnames RosuvastatinView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.