Desonide and Glycerol phenylbutyrate interaction

Desonide and Glycerol phenylbutyrate: the Glycerol phenylbutyrate prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Glycerol phenylbutyrate label · effective 2025-06-30

Moderate

Corticosteroids, valproic acid, or haloperidol : May increase plasma ammonia level; monitor ammonia levels closely.

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Moderate

Potential for Other Drugs to Affect Ammonia Corticosteroids Use of corticosteroids may cause the breakdown of body protein and increase plasma ammonia levels.

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Moderate

Monitor ammonia levels closely when corticosteroids and glycerol phenylbutyrate are used concomitantly.

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Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.