Diazepam and Naproxen and esomeprazole interaction

Diazepam and Naproxen and esomeprazole: the Naproxen and esomeprazole prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Naproxen and esomeprazole (Naproxen and esomeprazole magnesium) label · effective 2026-05-27

Moderate

Diazepam Clinical Impact: Increased exposure of diazepam [see Clinical Pharmacology (12.3) ].

Drug interactionsnames DiazepamView label on DailyMed
Moderate

Intervention: Monitor patients for increased sedation and adjust the dose of diazepam as needed.

Drug interactionsnames DiazepamView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.