Diethylpropion and Propofol interaction

Diethylpropion and Propofol: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Diethylpropion (Diethylpropion Hydrochloride ER) label · effective 2026-05-29

Moderate

Concurrent use with general anesthetics may result in arrhythmias.

Drug interactionsby drug classView label on DailyMed

From the Propofol (Diprivan) label · effective 2025-09-10

Minor

These effects are responsive to discontinuation of DIPRIVAN, intravenous fluid administration, and/or vasopressor therapy.

Warnings and precautionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.