Dimenhydrinate and Pimozide interaction

Dimenhydrinate and Pimozide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Dimenhydrinate label · effective 2025-01-15

Moderate

The concomitant use of alcohol or other central nervous system depressants may have an additive effect.

Warningsby drug classView label on DailyMed

From the Pimozide label · effective 2026-08-12

Moderate

Other important considerations in the differential diagnosis include central anticholinergic toxicity, heat stroke, drug fever and primary central nervous system (CNS) pathology.

Warningsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.