Donepezil and Olanzapine interaction

Donepezil and Olanzapine: the Donepezil prescribing label mention this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Donepezil (Aricept) label · effective 2021-12-30

Minor

Cholinesterase inhibitors have the potential to interfere with the activity of anticholinergic medications ( 7.1 )

Drug interactionsby drug classView label on DailyMed
Minor

Use with Anticholinergics Because of their mechanism of action, cholinesterase inhibitors have the potential to interfere with the activity of anticholinergic medications.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.