Doxylamine and pyridoxine and Isosorbide dinitrate and hydralazine interaction

Doxylamine and pyridoxine and Isosorbide dinitrate and hydralazine: the Isosorbide dinitrate and hydralazine prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Isosorbide dinitrate and hydralazine (Isosorbide dinitrate and hydralazine hydrochloride) label · effective 2025-06-03

Minor

Peripheral Neuritis: May be treated with Pyridoxine ( 5.4 )

Warnings and precautionsnames Doxylamine and pyridoxineView label on DailyMed
Minor

Pyridoxine should be added to isosorbide dinitrate and hydralazine hydrochloride tablets therapy if such symptoms develop.

Warnings and precautionsnames Doxylamine and pyridoxineView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.