Dutasteride and Itraconazole interaction

Dutasteride and Itraconazole: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Itraconazole (Tolsura) label · effective 2025-04-23

Moderate

Dutasteride Oxybutynin Sildenafil (for erectile dysfunction) Tadalafil (for erectile dysfunction and benign prostatic hyperplasia) Tolterodine Monitor for adverse reactions.

Drug interactionsnames DutasterideView label on DailyMed

From the Dutasteride label · effective 2026-01-13

Minor

The effect of potent CYP3A4 inhibitors on dutasteride has not been studied.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.