Econazole and Efavirenz interaction

Econazole and Efavirenz: the Efavirenz prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Efavirenz label · effective 2024-03-31

Moderate

Antifungals: Voriconazole Itraconazole Ketoconazole Posaconazole ↓ voriconazole * ↑ efavirenz * ↓ itraconazole * ↓ hydroxyitraconazole * ↓ ketoconazole ↓ posaconazole * Efavirenz and voriconazole should not be coadministered at standard doses.

Drug interactionsby drug classView label on DailyMed
Moderate

Consider alternative antifungal treatment because no dose recommendation for itraconazole can be made.

Drug interactionsby drug classView label on DailyMed
Moderate

Consider alternative antifungal treatment because no dose recommendation for ketoconazole can be made.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.