Enalapril and Lithium interaction

Enalapril and Lithium: the Enalapril prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Enalapril (Enalapril maleate) label · effective 2025-12-16

Moderate

Monitor serum lithium levels frequently ( 7.4 ).

Drug interactionsnames LithiumView label on DailyMed
Moderate

Lithium Lithium toxicity has been reported in patients receiving enalapril and lithium concomitantly which was generally reversible.

Drug interactionsnames LithiumView label on DailyMed
Moderate

It is recommended that serum lithium levels be monitored frequently if enalapril is administered concomitantly with lithium.

Drug interactionsnames LithiumView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.