Enalaprilat and Lithium interaction

Enalaprilat and Lithium: the Enalaprilat prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Enalaprilat label · effective 2024-01-04

Moderate

Lithium Lithium toxicity has been reported in patients receiving lithium concomitantly with drugs which cause elimination of sodium, including ACE inhibitors.

Drug interactionsnames LithiumView label on DailyMed
Moderate

A few cases of lithium toxicity have been reported in patients receiving concomitant enalapril and lithium and were reversible upon discontinuation of both drugs.

Drug interactionsnames LithiumView label on DailyMed
Moderate

It is recommended that serum lithium levels be monitored frequently if enalapril is administered concomitantly with lithium.

Drug interactionsnames LithiumView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.