Epoprostenol and Isosorbide mononitrate interaction

Epoprostenol and Isosorbide mononitrate: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Epoprostenol (Veletri) label · effective 2022-11-28

Moderate

Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators.

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Moderate

Diuretics, antihypertensive agents, or other vasodilators : reduction in blood pressure ( 7 )

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From the Isosorbide mononitrate label · effective 2019-11-01

Moderate

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators.

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Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.