Erythromycin and Thioridazine interaction

Erythromycin and Thioridazine: the Thioridazine prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Thioridazine (Thioridazine Hydrochloride) label · effective 2026-03-02

Major

CONTRAINDICATIONS Thioridazine hydrochloride tablet use should be avoided in combination with other drugs that are known to prolong the QTc interval and in patients with congenital long QT syndrome or a history of cardiac arrhythmias.

Contraindicationsby drug classView label on DailyMed
Major

Such an increased risk may result also from the additive effect of coadministering thioridazine with other agents that prolong the QTc interval.

Contraindicationsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.