Eslicarbazepine and Ethosuximide interaction

Eslicarbazepine and Ethosuximide: the Eslicarbazepine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Eslicarbazepine (Aptiom) label · effective 2023-11-10

Moderate

Anyone considering prescribing APTIOM or any other AED must balance this risk with the risk of untreated illness.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Other Antiepileptic Drugs Several AEDs (e.g., carbamazepine, phenobarbital, phenytoin, and primidone) can induce enzymes that metabolize APTIOM and can cause decreased plasma concentrations of eslicarbazepine [see Clinical Pharmacology ( 12.3 )].

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.