Eslicarbazepine and Nintedanib interaction

Eslicarbazepine and Nintedanib: the Nintedanib prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Nintedanib (Ofev) label · effective 2025-11-20

Moderate

Coadministration with oral doses of a P-gp and CYP3A4 inducer, rifampicin, decreased exposure to nintedanib by 50%.

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Minor

Concomitant use of P-gp and CYP3A4 inducers (e.g., carbamazepine, phenytoin, and St.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.