Esmolol and Formoterol interaction

Esmolol and Formoterol: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Esmolol (BREVIBLOC) label · effective 2025-03-14

Moderate

Sympathomimetic drugs: Dose adjustment needed ( 7 )

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Minor

• Sympathomimetic drugs: Sympathomimetic drugs having beta-adrenergic agonist activity will counteract effects of BREVIBLOC injection.

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From the Formoterol (FORMOTEROL FUMARATE) label · effective 2020-12-15

Moderate

Beta-blockers may decrease effectiveness.

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Moderate

In this setting, cardioselective beta-blockers could be considered, although they should be administered with caution.

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Minor

Beta-blockers Beta-adrenergic receptor antagonists (beta-blockers) and formoterol may inhibit the effect of each other when administered concurrently.

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Minor

Beta-blockers not only block the therapeutic effects of beta-agonists, but may produce severe bronchospasm in COPD patients.

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Minor

Therefore, patients with COPD should not normally be treated with beta-blockers.

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Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.